# Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment

> **NCT06104280** · — · RECRUITING · sponsor: **University of Alabama at Birmingham** · enrollment: 200 (estimated)

## Conditions studied

- Opioid Use Disorder
- Sleep Disturbance

## Interventions

- **OTHER:** Post-Illumination Pupillary Response (PIPR)
- **OTHER:** Polysomnography
- **OTHER:** Multiple Sleep Latency Test
- **BEHAVIORAL:** Ecological Momentary Assessments
- **DEVICE:** Actigraphy
- **OTHER:** DLMO
- **OTHER:** Melatonin Suppression Test

## Key facts

- **NCT ID:** NCT06104280
- **Lead sponsor:** University of Alabama at Birmingham
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2025-01-06
- **Primary completion:** 2028-12-28
- **Final completion:** 2029-01-01
- **Target enrollment:** 200 (ESTIMATED)
- **Last updated:** 2026-05-07

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06104280

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06104280, "Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment". Retrieved via AI Analytics 2026-08-15 from https://api.ai-analytics.org/clinical/NCT06104280. Licensed CC0.

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