# Perioperative Vitamin C to Reduce Persistent Pain After Total Knee Arthroplasty

> **NCT06123715** · PHASE2 · RECRUITING · sponsor: **University Health Network, Toronto** · enrollment: 300 (estimated)

## Conditions studied

- Chronic Pain
- Knee Pain Chronic
- Post Operative Pain

## Interventions

- **DRUG:** Vitamin C
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT06123715
- **Lead sponsor:** University Health Network, Toronto
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-04-16
- **Primary completion:** 2025-12-31
- **Final completion:** 2026-12-31
- **Target enrollment:** 300 (ESTIMATED)
- **Last updated:** 2025-04-25

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06123715

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06123715, "Perioperative Vitamin C to Reduce Persistent Pain After Total Knee Arthroplasty". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT06123715. Licensed CC0.

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