Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome
Conditions
- Acute Lymphoblastic Leukemia
- Acute Myeloid Leukemia
- Myelodysplastic Syndrome
Interventions
- PROCEDURE: Biospecimen Collection
- PROCEDURE: Chest Computed Tomography
- PROCEDURE: Echocardiography
- PROCEDURE: Hematopoietic Cell Transplantation
- DRUG: Methotrexate
- PROCEDURE: Multigated Acquisition Scan
- DRUG: Ruxolitinib Phosphate
- DRUG: Tacrolimus
Sponsor
City of Hope Medical Center
Collaborators