# Pure Florid and Pleomorphic Lobular Carcinoma in Situ of the Breast: Towards an Increasingly Uniform Management

> **NCT06133465** · — · COMPLETED · sponsor: **Istituto Oncologico Veneto IRCCS** · enrollment: 1063 (actual)

## Conditions studied

- Pleomorphic Lobular Breast Carcinoma in Situ
- Breast Florid Lobular Carcinoma in Situ

## Interventions

- **PROCEDURE:** Surgical wide local excision
- **PROCEDURE:** Cavity shaving
- **PROCEDURE:** Excision margin surgical clearance
- **RADIATION:** Adjuvant Radiotherapy
- **BIOLOGICAL:** Adjuvant Hormone Therapy

## Key facts

- **NCT ID:** NCT06133465
- **Lead sponsor:** Istituto Oncologico Veneto IRCCS
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2023-10-15
- **Primary completion:** 2024-12-31
- **Final completion:** 2025-01-31
- **Target enrollment:** 1063 (ACTUAL)
- **Last updated:** 2026-04-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06133465

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06133465, "Pure Florid and Pleomorphic Lobular Carcinoma in Situ of the Breast: Towards an Increasingly Uniform Management". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT06133465. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*