# The Impact of Working Memory and Reward Markers on DLPFC Activity in Treatment-resistant Depression

> **NCT06163625** · NA · RECRUITING · sponsor: **Unity Health Toronto** · enrollment: 50 (estimated)

## Conditions studied

- Major Depressive Disorder
- Treatment Resistant Depression

## Interventions

- **DEVICE:** Repetitive Transcranial Magnetic Stimulation
- **BEHAVIORAL:** Research Interview, Questionnaires
- **BEHAVIORAL:** Brain Scan
- **BIOLOGICAL:** Saliva Samples

## Key facts

- **NCT ID:** NCT06163625
- **Lead sponsor:** Unity Health Toronto
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-01
- **Primary completion:** 2026-12-31
- **Final completion:** 2026-12-31
- **Target enrollment:** 50 (ESTIMATED)
- **Last updated:** 2024-12-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06163625

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06163625, "The Impact of Working Memory and Reward Markers on DLPFC Activity in Treatment-resistant Depression". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT06163625. Licensed CC0.

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