# A Randomized Controlled Trial of Vitamin D Supplementation on Salivary Biomarkers and Cariogenic Oral Microbiome

> **NCT06172764** · PHASE4 · RECRUITING · sponsor: **Dow University of Health Sciences** · enrollment: 90 (estimated)

## Conditions studied

- Dental Caries
- White Spot Lesion
- Initial Caries
- Incipient Enamel Caries

## Interventions

- **DIETARY_SUPPLEMENT:** Vitamin D supplements along with behavioral modification
- **COMBINATION_PRODUCT:** Topical fluoride application and Vitamin D supplements along with behavioral modification
- **PROCEDURE:** Topical fluoride application along with behavioral modification

## Key facts

- **NCT ID:** NCT06172764
- **Lead sponsor:** Dow University of Health Sciences
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-12-12
- **Primary completion:** 2025-10
- **Final completion:** 2025-12
- **Target enrollment:** 90 (ESTIMATED)
- **Last updated:** 2025-03-11

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06172764

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06172764, "A Randomized Controlled Trial of Vitamin D Supplementation on Salivary Biomarkers and Cariogenic Oral Microbiome". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06172764. Licensed CC0.

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