# Safety and Efficacy of Thermosensitive Hydroxybutyl Chitosan and 5-fluorouracil Assisted Endoscopic Dacryocystorhinostomy in the Treatment of Chronic Dacryocystitis

> **NCT06175676** · PHASE1 · COMPLETED · sponsor: **Tianjin Medical University Eye Hospital** · enrollment: 90 (actual)

## Conditions studied

- Dacryocystorhinostomy
- Hydroxybutyl Chitosan
- Fluorouracil
- Chronic Dacryocystitis

## Interventions

- **DRUG:** Hydroxybutyl chitosan
- **DRUG:** 5-Fluorouracil
- **DRUG:** Gelatin Sponge Sheet

## Key facts

- **NCT ID:** NCT06175676
- **Lead sponsor:** Tianjin Medical University Eye Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-12-03
- **Primary completion:** 2023-06-30
- **Final completion:** 2023-12-03
- **Target enrollment:** 90 (ACTUAL)
- **Last updated:** 2023-12-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06175676

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06175676, "Safety and Efficacy of Thermosensitive Hydroxybutyl Chitosan and 5-fluorouracil Assisted Endoscopic Dacryocystorhinostomy in the Treatment of Chronic Dacryocystitis". Retrieved via AI Analytics 2026-06-04 from https://api.ai-analytics.org/clinical/NCT06175676. Licensed CC0.

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