# Trial Evaluating the Rate of Pneumothorax in Severe Emphysema Secondary to Endoscopic Volume Reduction With Two-stage ZEPHYR® Valves Versus Endoscopic Volume Reduction With One-stage ZEPHYR® Valves

> **NCT06181357** · NA · RECRUITING · sponsor: **University Hospital, Limoges** · enrollment: 244 (estimated)

## Conditions studied

- COPD

## Interventions

- **PROCEDURE:** Endoscopic lung volume reduction in 2 stages
- **PROCEDURE:** Endoscopic lung volume reduction in 1 stage

## Key facts

- **NCT ID:** NCT06181357
- **Lead sponsor:** University Hospital, Limoges
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-05-06
- **Primary completion:** 2027-06-06
- **Final completion:** 2027-06-06
- **Target enrollment:** 244 (ESTIMATED)
- **Last updated:** 2025-03-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06181357

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06181357, "Trial Evaluating the Rate of Pneumothorax in Severe Emphysema Secondary to Endoscopic Volume Reduction With Two-stage ZEPHYR® Valves Versus Endoscopic Volume Reduction With One-stage ZEPHYR® Valves". Retrieved via AI Analytics 2026-07-17 from https://api.ai-analytics.org/clinical/NCT06181357. Licensed CC0.

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