# COLDFIRE-III Trial: Efficacy of Irreversible Electroporation and Stereotactic Body Radiotherapy for Perivascular and Peribiliary Colorectal Liver Metastases

> **NCT06185556** · PHASE2,PHASE3 · RECRUITING · sponsor: **Amsterdam UMC, location VUmc** · enrollment: 78 (estimated)

## Conditions studied

- Colorectal Cancer
- Liver Metastases
- Liver Metastasis Colon Cancer
- Unresectable Solid Tumor

## Interventions

- **PROCEDURE:** Irreversible electroporation
- **RADIATION:** Stereotactic body radiotherapy

## Key facts

- **NCT ID:** NCT06185556
- **Lead sponsor:** Amsterdam UMC, location VUmc
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-08-20
- **Primary completion:** 2029-09-01
- **Final completion:** 2031-09-01
- **Target enrollment:** 78 (ESTIMATED)
- **Last updated:** 2024-08-23

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06185556

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06185556, "COLDFIRE-III Trial: Efficacy of Irreversible Electroporation and Stereotactic Body Radiotherapy for Perivascular and Peribiliary Colorectal Liver Metastases". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT06185556. Licensed CC0.

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