Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells

NCT06186401 · clinicaltrials.gov ↗

PHASE1

Phase

RECRUITING

Status

20

Enrollment

OTHER

Sponsor class

Conditions

EGFR Gene Mutation
Glioblastoma
MGMT-Unmethylated Glioblastoma
Recurrent Glioblastoma

Interventions

BIOLOGICAL: E-SYNC T Cells
DRUG: Cyclophosphamide (non-investigational)
DRUG: Fludarabine (non-investigational)
PROCEDURE: Leukapheresis
PROCEDURE: Surgical resection

Sponsor

Hideho Okada, MD, PhD

Collaborators

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