# Superiority of On-demand PrEP Versus PEP on Using Doxycycline for Preventing STI in MSM

> **NCT06188442** · PHASE4 · RECRUITING · sponsor: **Chinese University of Hong Kong** · enrollment: 300 (estimated)

## Conditions studied

- Sexually Transmitted Diseases, Bacterial
- Syphilis
- Gonorrhea
- Chlamydia

## Interventions

- **DRUG:** DoxyODPrEP
- **DRUG:** DoxyPEP

## Key facts

- **NCT ID:** NCT06188442
- **Lead sponsor:** Chinese University of Hong Kong
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-03-29
- **Primary completion:** 2027-12-31
- **Final completion:** 2028-12
- **Target enrollment:** 300 (ESTIMATED)
- **Last updated:** 2025-04-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06188442

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06188442, "Superiority of On-demand PrEP Versus PEP on Using Doxycycline for Preventing STI in MSM". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT06188442. Licensed CC0.

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