# Impact of Advanced Platelet Rich Fibrin and Enamel Matrix Derivative on Clinical and Molecular Wound Healing Parameters After Surgical Removal of Mandibular Third Molars

> **NCT06190015** · PHASE4 · UNKNOWN · sponsor: **University of Belgrade** · enrollment: 120 (actual)

## Conditions studied

- Surgical Wound, Healed
- Post Operative Pain

## Interventions

- **BIOLOGICAL:** Advanced platelet rich fibrin (APRF) clots
- **DEVICE:** Enamel matrix derivative (EMD) group

## Key facts

- **NCT ID:** NCT06190015
- **Lead sponsor:** University of Belgrade
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2022-05-23
- **Primary completion:** 2024-01-20
- **Final completion:** 2024-03-20
- **Target enrollment:** 120 (ACTUAL)
- **Last updated:** 2024-01-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06190015

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06190015, "Impact of Advanced Platelet Rich Fibrin and Enamel Matrix Derivative on Clinical and Molecular Wound Healing Parameters After Surgical Removal of Mandibular Third Molars". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT06190015. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*