# Neurocognitive Mechanisms of Perimenstrual Estrogen Effects on Suicidality

> **NCT06191289** · PHASE2 · TERMINATED · sponsor: **University of Illinois at Chicago** · enrollment: 11 (actual)

## Conditions studied

- Suicide

## Interventions

- **DRUG:** Transdermal Estradiol
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT06191289
- **Lead sponsor:** University of Illinois at Chicago
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2024-03-16
- **Primary completion:** 2024-12-01
- **Final completion:** 2024-12-01
- **Target enrollment:** 11 (ACTUAL)
- **Why stopped:** Funding changes necessitated the preliminary conclusion of the study; it will be used for feasibility data.
- **Last updated:** 2025-10-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06191289

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06191289, "Neurocognitive Mechanisms of Perimenstrual Estrogen Effects on Suicidality". Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/clinical/NCT06191289. Licensed CC0.

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