# The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder

> **NCT06203015** · — · UNKNOWN · sponsor: **Lithuanian University of Health Sciences** · enrollment: 150 (estimated)

## Conditions studied

- Major Depressive Disorder
- Inflammation
- Cognitive Dysfunction
- Endotoxemia
- Genetic Predisposition to Disease
- Blood Brain Barrier Defect

## Interventions

- **DIAGNOSTIC_TEST:** The Cambridge Neuropsychological Test Automated Battery.
- **DIAGNOSTIC_TEST:** Venous blood samples
- **DIAGNOSTIC_TEST:** brain MRI
- **DIAGNOSTIC_TEST:** the Montgomery-Åsberg Depression Rating Scale
- **OTHER:** questionnaire prepared by the researchers

## Key facts

- **NCT ID:** NCT06203015
- **Lead sponsor:** Lithuanian University of Health Sciences
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** UNKNOWN
- **Start date:** 2022-06-01
- **Primary completion:** 2024-06-01
- **Final completion:** 2024-06-01
- **Target enrollment:** 150 (ESTIMATED)
- **Last updated:** 2024-01-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06203015

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06203015, "The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT06203015. Licensed CC0.

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