Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer

NCT06236139 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

RECRUITING

Status

48

Enrollment

OTHER

Sponsor class

Conditions

Castration-Resistant Prostate Carcinoma
Metastatic Prostate Adenocarcinoma
Stage IVB Prostate Cancer AJCC v8

Interventions

BIOLOGICAL: Anti-STEAP1 CAR T-cells
PROCEDURE: Biopsy
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Scan
PROCEDURE: Computed Tomography
DRUG: Cyclophosphamide
PROCEDURE: Echocardiography
DRUG: Enzalutamide
DRUG: Fludarabine
PROCEDURE: Leukapheresis
PROCEDURE: Magnetic Resonance Imaging
PROCEDURE: Multigated Acquisition Scan
PROCEDURE: Positron Emission Tomography

Sponsor

Fred Hutchinson Cancer Center

Collaborators

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