# Comparison of Guiding Sedation Level by Respiratory Effort Versus Usual Care in Mechanically Ventilated Patients: A Randomized Controlled Trial (EFFORT-GUIDE Trial 2)

> **NCT06242236** · NA · COMPLETED · sponsor: **Ramathibodi Hospital** · enrollment: 156 (actual)

## Conditions studied

- ARDS
- Respiratory Effort
- Mechanical Ventilation Complication
- Sedation

## Interventions

- **OTHER:** The respiratory effort parameters guide sedative dosage.

## Key facts

- **NCT ID:** NCT06242236
- **Lead sponsor:** Ramathibodi Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-10-01
- **Primary completion:** 2024-10-31
- **Final completion:** 2025-06-30
- **Target enrollment:** 156 (ACTUAL)
- **Last updated:** 2025-07-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06242236

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06242236, "Comparison of Guiding Sedation Level by Respiratory Effort Versus Usual Care in Mechanically Ventilated Patients: A Randomized Controlled Trial (EFFORT-GUIDE Trial 2)". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06242236. Licensed CC0.

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