Adaptive Boost Radiotherapy to Primary Lesions and Positive Nodes in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer

Stopped The study was terminated early for futility based on the interim analysis. The results indicated a low probability of achieving the primary endpoint.

Conditions

• Rectal Cancer

Interventions

• RADIATION: Adaptive Boost Radiotherapy
• RADIATION: Long course non-ART radiotherapy
• DRUG: Concurrent chemotherapy
• DRUG: Consolidation Chemotherapy
• PROCEDURE: Total mesorectal excision (TME) surgery

Sponsor

Shandong Cancer Hospital and Institute