Carfilzomib in Combination With Sotorasib for the Treatment of Patients With KRAS G12C Mutated Advanced or Metastatic Non-small Cell Lung Cancer

NCT06249282 · clinicaltrials.gov ↗

PHASE1

Phase

RECRUITING

Status

15

Enrollment

OTHER

Sponsor class

Conditions

Advanced Lung Non-Small Cell Carcinoma
Metastatic Lung Non-Small Cell Carcinoma
Stage III Lung Cancer AJCC v8
Stage IV Lung Cancer AJCC v8

Interventions

PROCEDURE: Biopsy
PROCEDURE: Biospecimen Collection
DRUG: Carfilzomib
PROCEDURE: Computed Tomography
PROCEDURE: Echocardiography
PROCEDURE: Magnetic Resonance Imaging
DRUG: Sotorasib

Sponsor

City of Hope Medical Center

Collaborators

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