# Evaluation of Rapid First-line Genome Sequencing for Prenatal Diagnosis of Congenital Malformations in Comparison With Chromosomal Microarray and Exome Sequencing

> **NCT06252415** · — · COMPLETED · sponsor: **Centre Hospitalier Universitaire Dijon** · enrollment: 184 (actual)

## Conditions studied

- Congenital Malformation

## Interventions

- **BIOLOGICAL:** foetal amniotic fluid sample
- **BIOLOGICAL:** blood samples
- **OTHER:** semi-structured online interviews

## Key facts

- **NCT ID:** NCT06252415
- **Lead sponsor:** Centre Hospitalier Universitaire Dijon
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2024-03-27
- **Primary completion:** 2025-07-22
- **Final completion:** 2025-07-22
- **Target enrollment:** 184 (ACTUAL)
- **Last updated:** 2026-01-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06252415

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06252415, "Evaluation of Rapid First-line Genome Sequencing for Prenatal Diagnosis of Congenital Malformations in Comparison With Chromosomal Microarray and Exome Sequencing". Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/clinical/NCT06252415. Licensed CC0.

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