# DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer

> **NCT06275958** · PHASE3 · RECRUITING · sponsor: **Leiden University Medical Center** · enrollment: 587 (estimated)

## Conditions studied

- Older Patients
- Colorectal Cancer
- Metastatic Cancer
- Candidates for Palliative Chemotherapy

## Interventions

- **DRUG:** Doublet Chemotherapy, Standard Dose (100%)
- **DRUG:** Doublet Chemotherapy, Dose-reduced (75%)
- **DRUG:** Monotherapy, Standard Dose (100%)
- **DRUG:** Monotherapy, Dose-reduced (75%)

## Key facts

- **NCT ID:** NCT06275958
- **Lead sponsor:** Leiden University Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-07-01
- **Primary completion:** 2028-06
- **Final completion:** 2028-12
- **Target enrollment:** 587 (ESTIMATED)
- **Last updated:** 2024-10-16

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06275958

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06275958, "DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT06275958. Licensed CC0.

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