# Efficacy and Safety of Sivelestat in Preventing Postoperative Acute Lung Injury or Acute Respiratory Distress Syndrome After Cardiac Surgery

> **NCT06276569** · PHASE3 · COMPLETED · sponsor: **The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School** · enrollment: 382 (actual)

## Conditions studied

- Cardiac Disease

## Interventions

- **DRUG:** Sivelestat
- **OTHER:** placebo

## Key facts

- **NCT ID:** NCT06276569
- **Lead sponsor:** The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2024-02-18
- **Primary completion:** 2025-04-30
- **Final completion:** 2025-07-30
- **Target enrollment:** 382 (ACTUAL)
- **Last updated:** 2025-08-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06276569

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06276569, "Efficacy and Safety of Sivelestat in Preventing Postoperative Acute Lung Injury or Acute Respiratory Distress Syndrome After Cardiac Surgery". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT06276569. Licensed CC0.

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