# Effects of Antihypertensive Drug Treatment on Brain Blood Flow, Cognition, and Regulation of Nervous System in Older Adults With Hypertension.

> **NCT06287580** · EARLY_PHASE1 · COMPLETED · sponsor: **University of Texas Southwestern Medical Center** · enrollment: 27 (actual)

## Conditions studied

- Essential Hypertension
- Older Adults

## Interventions

- **DRUG:** chlorthalidone
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT06287580
- **Lead sponsor:** University of Texas Southwestern Medical Center
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2024-08-15
- **Primary completion:** 2026-02-20
- **Final completion:** 2026-02-20
- **Target enrollment:** 27 (ACTUAL)
- **Last updated:** 2026-02-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06287580

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06287580, "Effects of Antihypertensive Drug Treatment on Brain Blood Flow, Cognition, and Regulation of Nervous System in Older Adults With Hypertension.". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT06287580. Licensed CC0.

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