# A First-in-Human Study to Learn How Well a Bi-Layer Calcium Carbonate Antacid Tablet Works Compared to a Standard, Non-Layered Calcium Carbonate Tablet in Healthy Male Participants

> **NCT06293326** · PHASE1 · COMPLETED · sponsor: **Bayer** · enrollment: 21 (actual)

## Conditions studied

- Heartburn
- Indigestion
- Stomach Acid Related Symptoms
- Nocturnal Stomach Acid Related Symptoms
- Healthy Volunteers

## Interventions

- **DRUG:** bi-layer calcium carbonate tablet (BAY1180654)
- **DRUG:** Immediate release calcium carbonate tablet (BAY1180654)

## Key facts

- **NCT ID:** NCT06293326
- **Lead sponsor:** Bayer
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2024-03-06
- **Primary completion:** 2024-05-15
- **Final completion:** 2024-05-15
- **Target enrollment:** 21 (ACTUAL)
- **Last updated:** 2024-07-03


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06293326

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06293326, "A First-in-Human Study to Learn How Well a Bi-Layer Calcium Carbonate Antacid Tablet Works Compared to a Standard, Non-Layered Calcium Carbonate Tablet in Healthy Male Participants". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT06293326. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*