# Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells

> **NCT06305299** · PHASE1 · RECRUITING · sponsor: **UNC Lineberger Comprehensive Cancer Center** · enrollment: 27 (estimated)

## Conditions studied

- Ovary Neoplasm
- Ovarian Cancer
- Epithelial Ovarian Cancer
- Recurrent

## Interventions

- **BIOLOGICAL:** iC9-CAR.B7-H3 T cells
- **DRUG:** Cyclophosphamide
- **DRUG:** Fludarabine

## Key facts

- **NCT ID:** NCT06305299
- **Lead sponsor:** UNC Lineberger Comprehensive Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-07-29
- **Primary completion:** 2036-04
- **Final completion:** 2036-04
- **Target enrollment:** 27 (ESTIMATED)
- **Last updated:** 2026-04-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06305299

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06305299, "Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT06305299. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*