# MID-STEP (MIDodrine for Sepsis Treatment and Early vasoPressor Weaning) Trial

> **NCT06319248** · PHASE2 · RECRUITING · sponsor: **Mayo Clinic** · enrollment: 308 (estimated)

## Conditions studied

- Sepsis
- Low Blood Pressure

## Interventions

- **DRUG:** Midodrine
- **OTHER:** Standard of Care

## Key facts

- **NCT ID:** NCT06319248
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-05-14
- **Primary completion:** 2029-05-30
- **Final completion:** 2029-07-30
- **Target enrollment:** 308 (ESTIMATED)
- **Last updated:** 2025-10-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06319248

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06319248, "MID-STEP (MIDodrine for Sepsis Treatment and Early vasoPressor Weaning) Trial". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT06319248. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
