# Prospective Multicenter Randomized and Controlled Study Evaluating the Benefit of Early Pulmonary Vein Isolation Compared to Usual Treatment in Patients Aged Over 75 Years and Presenting With Atrial Fibrillation

> **NCT06322017** · NA · RECRUITING · sponsor: **Nantes University Hospital** · enrollment: 294 (estimated)

## Conditions studied

- Atrial Fibrillation

## Interventions

- **PROCEDURE:** Rhythm control by Pulmonary Vein Isolation (PVI) procedure
- **DRUG:** Conventional care by antiarrhythmic drugs (flecainide, sotalol, amiodarone) or bradycardic drugs (all betablocker or calcium channel blocker therapy, digoxin)

## Key facts

- **NCT ID:** NCT06322017
- **Lead sponsor:** Nantes University Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-04-09
- **Primary completion:** 2030-04-09
- **Final completion:** 2030-04-09
- **Target enrollment:** 294 (ESTIMATED)
- **Last updated:** 2025-04-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06322017

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06322017, "Prospective Multicenter Randomized and Controlled Study Evaluating the Benefit of Early Pulmonary Vein Isolation Compared to Usual Treatment in Patients Aged Over 75 Years and Presenting With Atrial Fibrillation". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT06322017. Licensed CC0.

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