# Avapritinib With Decitabine in Patients With SM-AHN

> **NCT06327685** · PHASE1 · RECRUITING · sponsor: **H. Lee Moffitt Cancer Center and Research Institute** · enrollment: 34 (estimated)

## Conditions studied

- Systemic Mastocytosis With an Associated Hematologic Neoplasm

## Interventions

- **DRUG:** Avapritinib
- **DRUG:** Decitabine
- **COMBINATION_PRODUCT:** Decitabine/Cedazuridine

## Key facts

- **NCT ID:** NCT06327685
- **Lead sponsor:** H. Lee Moffitt Cancer Center and Research Institute
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-03-13
- **Primary completion:** 2027-03
- **Final completion:** 2027-03
- **Target enrollment:** 34 (ESTIMATED)
- **Last updated:** 2026-04-01

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06327685

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06327685, "Avapritinib With Decitabine in Patients With SM-AHN". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT06327685. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*