# Mechanisms of Pulmonary Vascular Dysfunction in Heart Failure

> **NCT06331208** · — · RECRUITING · sponsor: **Institute for Clinical and Experimental Medicine** · enrollment: 230 (estimated)

## Conditions studied

- Heart Failure
- Pulmonary Hypertension
- Pulmonary Vascular Resistance Abnormality

## Interventions

- **DIAGNOSTIC_TEST:** non-contrast chest CT
- **DIAGNOSTIC_TEST:** spirometry with diffusing lung capacity for carbon monoxide (DLCO) analysis
- **DIAGNOSTIC_TEST:** Omics analysis of blood plasma obtained from pulmonary artery or peripheral blood
- **DIAGNOSTIC_TEST:** supine bike exercise during right heart catheterisation
- **DIAGNOSTIC_TEST:** Lung ventilation/perfusion SPECT

## Key facts

- **NCT ID:** NCT06331208
- **Lead sponsor:** Institute for Clinical and Experimental Medicine
- **Sponsor class:** OTHER_GOV
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2024-08-23
- **Primary completion:** 2026-12-30
- **Final completion:** 2026-12-30
- **Target enrollment:** 230 (ESTIMATED)
- **Last updated:** 2024-08-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06331208

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06331208, "Mechanisms of Pulmonary Vascular Dysfunction in Heart Failure". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT06331208. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*