Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of 16055 NFL Delta Gly4 Env Protein Trimer and Trimer 4571 Combined With 3M-052-AF + Alum Adjuvant and Ad4-Env145NFL Viral Particles as Heterologous Prime-boost Regimens in Adult Participants Without HIV.

NCT06332339 · clinicaltrials.gov ↗

PHASE1

Phase

ACTIVE_NOT_RECRUITING

Status

45

Enrollment

NIH

Sponsor class

Conditions

HIV

Interventions

BIOLOGICAL: 16055 NFL delta Gly4 trimer
BIOLOGICAL: Trimer 4571
BIOLOGICAL: Ad4-Env145NFL, 5 x 108 viral particles (vp)

Sponsor

National Institute of Allergy and Infectious Diseases (NIAID)