# To Evaluate the Dose-response Effects of a Defined Volume of Physical Exercise on the Change of Peripheral Biomarkers, Clinical Response and Brain Connectivity in Parkinson's Disease: a Prospective, Observational, Cohort Pilot Study

> **NCT06339398** · — · RECRUITING · sponsor: **Casa di Cura San Raffaele Cassino** · enrollment: 30 (estimated)

## Conditions studied

- Parkinson Disease

## Interventions

- **BEHAVIORAL:** Aerobic exercise

## Key facts

- **NCT ID:** NCT06339398
- **Lead sponsor:** Casa di Cura San Raffaele Cassino
- **Sponsor class:** NETWORK
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2025-02-11
- **Primary completion:** 2027-12-31
- **Final completion:** 2028-05-31
- **Target enrollment:** 30 (ESTIMATED)
- **Last updated:** 2025-02-13

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06339398

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06339398, "To Evaluate the Dose-response Effects of a Defined Volume of Physical Exercise on the Change of Peripheral Biomarkers, Clinical Response and Brain Connectivity in Parkinson's Disease: a Prospective, Observational, Cohort Pilot Study". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT06339398. Licensed CC0.

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