# Topical Tretinoin Prophylaxis for Anti-EGFR Induced Skin Toxicity in Patients With Solid Tumors

> **NCT06358677** · PHASE2 · RECRUITING · sponsor: **University of Utah** · enrollment: 25 (estimated)

## Conditions studied

- Metastatic Solid Tumor
- Locally Advanced Solid Tumor

## Interventions

- **DRUG:** Topical Tretinoin
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT06358677
- **Lead sponsor:** University of Utah
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-02-19
- **Primary completion:** 2027-07
- **Final completion:** 2029-07
- **Target enrollment:** 25 (ESTIMATED)
- **Last updated:** 2026-02-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06358677

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06358677, "Topical Tretinoin Prophylaxis for Anti-EGFR Induced Skin Toxicity in Patients With Solid Tumors". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT06358677. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*