# Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers

> **NCT06372899** · NA · RECRUITING · sponsor: **Abramson Cancer Center at Penn Medicine** · enrollment: 200 (estimated)

## Conditions studied

- E-cigarette Use
- Cigarette Smoking
- Harm Reduction
- Tobacco Use

## Interventions

- **OTHER:** E-cigarettes
- **OTHER:** Oral nicotine pouches

## Key facts

- **NCT ID:** NCT06372899
- **Lead sponsor:** Abramson Cancer Center at Penn Medicine
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-10-02
- **Primary completion:** 2027-11
- **Final completion:** 2028-03-31
- **Target enrollment:** 200 (ESTIMATED)
- **Last updated:** 2026-03-12

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06372899

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06372899, "Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers". Retrieved via AI Analytics 2026-07-19 from https://api.ai-analytics.org/clinical/NCT06372899. Licensed CC0.

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