# Study of Injectable Naltrexone and Oral Bupropion Among Cigarette Smokers With Schizophrenia

> **NCT06374290** · PHASE1 · TERMINATED · sponsor: **The University of Texas Health Science Center, Houston** · enrollment: 2 (actual)

## Conditions studied

- Smoking Cessation

## Interventions

- **DRUG:** Naltrexone (Vivitrol)
- **DRUG:** Bupropion

## Key facts

- **NCT ID:** NCT06374290
- **Lead sponsor:** The University of Texas Health Science Center, Houston
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2024-07-16
- **Primary completion:** 2024-12-04
- **Final completion:** 2024-12-04
- **Target enrollment:** 2 (ACTUAL)
- **Why stopped:** Unable to recruit eligible participants and expiration of study medication.
- **Last updated:** 2025-09-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06374290

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06374290, "Study of Injectable Naltrexone and Oral Bupropion Among Cigarette Smokers With Schizophrenia". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT06374290. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
