# Effectiveness of Screening and Decolonization of S. Aureus to Prevent S. Aureus Surgical Site Infections in Surgery Outpatients

> **NCT06378359** · — · RECRUITING · sponsor: **University of Minnesota** · enrollment: 250 (estimated)

## Conditions studied

- Staphylococcus Aureus Colonization
- Surgical Site Infections
- Healthcare Associated Infections

## Interventions

- **OTHER:** Screening and decolonization for SA carriers with the 3 drug bundle
- **OTHER:** No screening for SA
- **OTHER:** no screening
- **OTHER:** Nasal povidone-iodine on surgery day plus 2 CHG pre-op showers without screening.
- **OTHER:** Nasal alcohol gel on surgery day plus 2 CHG pre-op showers without screening

## Key facts

- **NCT ID:** NCT06378359
- **Lead sponsor:** University of Minnesota
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2024-01-29
- **Primary completion:** 2026-12-31
- **Final completion:** 2026-12-31
- **Target enrollment:** 250 (ESTIMATED)
- **Last updated:** 2026-01-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06378359

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06378359, "Effectiveness of Screening and Decolonization of S. Aureus to Prevent S. Aureus Surgical Site Infections in Surgery Outpatients". Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/clinical/NCT06378359. Licensed CC0.

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