# A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital Herpes

> **NCT06385327** · PHASE1 · COMPLETED · sponsor: **Assembly Biosciences** · enrollment: 115 (actual)

## Conditions studied

- Recurrent Genital Herpes Simplex Type 2

## Interventions

- **DRUG:** ABI-5366
- **DRUG:** ABI-5366 Placebo

## Key facts

- **NCT ID:** NCT06385327
- **Lead sponsor:** Assembly Biosciences
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2024-05-30
- **Primary completion:** 2026-02-03
- **Final completion:** 2026-02-03
- **Target enrollment:** 115 (ACTUAL)
- **Last updated:** 2026-03-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06385327

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06385327, "A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital Herpes". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT06385327. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*