# A Study to Evaluate HMPL-306 in Patients With IDH1or IDH2-mutated Acute Myeloid Leukemia

> **NCT06387069** · PHASE3 · RECRUITING · sponsor: **Hutchmed** · enrollment: 316 (estimated)

## Conditions studied

- Acute Myeloid Leukemia

## Interventions

- **DRUG:** HMPL-306 Regimen
- **DRUG:** Salvage Chemotherapy Regimen

## Key facts

- **NCT ID:** NCT06387069
- **Lead sponsor:** Hutchmed
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-04-26
- **Primary completion:** 2028-12-31
- **Final completion:** 2029-09-30
- **Target enrollment:** 316 (ESTIMATED)
- **Last updated:** 2025-08-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06387069

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06387069, "A Study to Evaluate HMPL-306 in Patients With IDH1or IDH2-mutated Acute Myeloid Leukemia". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT06387069. Licensed CC0.

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