# Pain Control and Quality of Recovery After Intravenous Methadone Versus Intrathecal Morphine in Major Abdominal Surgery

> **NCT06387303** · EARLY_PHASE1 · RECRUITING · sponsor: **University of Virginia** · enrollment: 40 (estimated)

## Conditions studied

- Pain, Postoperative

## Interventions

- **DRUG:** Methadone
- **DRUG:** Morphine

## Key facts

- **NCT ID:** NCT06387303
- **Lead sponsor:** University of Virginia
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-08-06
- **Primary completion:** 2026-05-11
- **Final completion:** 2026-05-11
- **Target enrollment:** 40 (ESTIMATED)
- **Last updated:** 2025-08-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06387303

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06387303, "Pain Control and Quality of Recovery After Intravenous Methadone Versus Intrathecal Morphine in Major Abdominal Surgery". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT06387303. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
