# APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia

> **NCT06408181** · PHASE3 · RECRUITING · sponsor: **University of Pennsylvania** · enrollment: 1150 (estimated)

## Conditions studied

- Pre-Eclampsia
- Pregnancy Loss

## Interventions

- **DRUG:** Aspirin 162 mg
- **DRUG:** Aspirin 81mg

## Key facts

- **NCT ID:** NCT06408181
- **Lead sponsor:** University of Pennsylvania
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-06-12
- **Primary completion:** 2029-06
- **Final completion:** 2029-06
- **Target enrollment:** 1150 (ESTIMATED)
- **Last updated:** 2026-01-20

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06408181

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06408181, "APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT06408181. Licensed CC0.

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