# A Comparative Effectiveness Study in Heart Transplant Patients of Rejection Surveillance With Cell-free DNA Versus Endomyocardial Biopsy

> **NCT06414603** · NA · ACTIVE_NOT_RECRUITING · sponsor: **Natera, Inc.** · enrollment: 250 (estimated)

## Conditions studied

- Heart Transplant Failure and Rejection

## Interventions

- **DIAGNOSTIC_TEST:** The Prospera™ Test

## Key facts

- **NCT ID:** NCT06414603
- **Lead sponsor:** Natera, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2024-06-10
- **Primary completion:** 2027-02
- **Final completion:** 2027-02
- **Target enrollment:** 250 (ESTIMATED)
- **Last updated:** 2026-02-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06414603

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06414603, "A Comparative Effectiveness Study in Heart Transplant Patients of Rejection Surveillance With Cell-free DNA Versus Endomyocardial Biopsy". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06414603. Licensed CC0.

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