# Short-course Radiotherapy or Long-course Chemoradiation Followed by mFOLFOXIRI Consolidation Chemotherapy for Organ Preservation in Low Rectal Cancer

> **NCT06417476** · PHASE2 · ACTIVE_NOT_RECRUITING · sponsor: **Pei-Rong Ding** · enrollment: 66 (estimated)

## Conditions studied

- Rectal Neoplasms

## Interventions

- **RADIATION:** Short-course radiotherapy
- **DRUG:** Irinotecan
- **DRUG:** Oxaliplatin
- **DRUG:** Calcium Formate
- **DRUG:** Fluorouracil
- **RADIATION:** Long-course chemoradiation
- **DRUG:** Capecitabine

## Key facts

- **NCT ID:** NCT06417476
- **Lead sponsor:** Pei-Rong Ding
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2022-12-12
- **Primary completion:** 2025-09-30
- **Final completion:** 2026-12-30
- **Target enrollment:** 66 (ESTIMATED)
- **Last updated:** 2026-04-13

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06417476

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06417476, "Short-course Radiotherapy or Long-course Chemoradiation Followed by mFOLFOXIRI Consolidation Chemotherapy for Organ Preservation in Low Rectal Cancer". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06417476. Licensed CC0.

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