# Clinical and Microbiological Evaluation of Laser Therapy in the Treatment of Periodontal Disease in Stages III and IV

> **NCT06426550** · NA · COMPLETED · sponsor: **Universidade Federal Fluminense** · enrollment: 20 (actual)

## Conditions studied

- Periodontitis
- Periodontitis, Adult

## Interventions

- **PROCEDURE:** Antimicrobial photodynamic therapy and 0.005% methylene blue (PDT)
- **PROCEDURE:** Photobiomodulation with a red laser (PBM-RL)
- **PROCEDURE:** Saline solution
- **PROCEDURE:** Photobiomodulation with an infrared laser (PBM-IRL)

## Key facts

- **NCT ID:** NCT06426550
- **Lead sponsor:** Universidade Federal Fluminense
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2024-05-06
- **Primary completion:** 2026-01-26
- **Final completion:** 2026-02-02
- **Target enrollment:** 20 (ACTUAL)
- **Last updated:** 2026-02-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06426550

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06426550, "Clinical and Microbiological Evaluation of Laser Therapy in the Treatment of Periodontal Disease in Stages III and IV". Retrieved via AI Analytics 2026-07-13 from https://api.ai-analytics.org/clinical/NCT06426550. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
