# A Safety and Feasibility Trial Protocol of Metformin in Infants After Perinatal Brain Injury

> **NCT06429007** · PHASE1 · ENROLLING_BY_INVITATION · sponsor: **Boston Children's Hospital** · enrollment: 30 (estimated)

## Conditions studied

- Hypoxic-Ischemic Encephalopathy
- HIE
- Neurodevelopment
- Infant Development

## Interventions

- **DRUG:** Metformin

## Key facts

- **NCT ID:** NCT06429007
- **Lead sponsor:** Boston Children's Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ENROLLING_BY_INVITATION
- **Start date:** 2025-10-01
- **Primary completion:** 2028-01-01
- **Final completion:** 2029-03-01
- **Target enrollment:** 30 (ESTIMATED)
- **Last updated:** 2026-02-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06429007

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06429007, "A Safety and Feasibility Trial Protocol of Metformin in Infants After Perinatal Brain Injury". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT06429007. Licensed CC0.

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