# A Block-and-Replace Therapy With Osilodrostat and Concomitant Glucocorticoid Replacement

> **NCT06430528** · — · RECRUITING · sponsor: **University of Michigan** · enrollment: 12 (estimated)

## Conditions studied

- Endogenous Cushing Syndrome
- Adrenal Insufficiency
- Hypercortisolism

## Interventions

- **DRUG:** Osilodrostat

## Key facts

- **NCT ID:** NCT06430528
- **Lead sponsor:** University of Michigan
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2024-07-19
- **Primary completion:** 2027-05
- **Final completion:** 2027-08
- **Target enrollment:** 12 (ESTIMATED)
- **Last updated:** 2025-08-20

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06430528

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06430528, "A Block-and-Replace Therapy With Osilodrostat and Concomitant Glucocorticoid Replacement". Retrieved via AI Analytics 2026-07-16 from https://api.ai-analytics.org/clinical/NCT06430528. Licensed CC0.

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