Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation
Conditions
- Thyroid Gland Follicular Carcinoma
- Thyroid Gland Oncocytic Carcinoma
- Thyroid Gland Papillary Carcinoma
Interventions
- PROCEDURE: Biospecimen Collection
- DRUG: Cobimetinib
- PROCEDURE: Computed Tomography
- PROCEDURE: Diagnostic Imaging
- PROCEDURE: I-131 Uptake Test
- RADIATION: Iodine I-131
- PROCEDURE: Magnetic Resonance Imaging
- PROCEDURE: Positron Emission Tomography
- BIOLOGICAL: Recombinant Thyrotropin Alfa
- PROCEDURE: Ultrasound Imaging
- DRUG: Vemurafenib
Sponsor
City of Hope Medical Center
Collaborators