# Mosaic HIV-1 Envelope Trimer Immunogens Administered to People Living with HIV (PLWH) in Africa

> **NCT06449196** · EARLY_PHASE1 · WITHDRAWN · sponsor: **International AIDS Vaccine Initiative**

## Conditions studied

- HIV

## Interventions

- **DRUG:** Investigational product HIV Env Mosaic immunogens MOS1SIP, MOS2SIP, M3SIP8 and Monophosphoryl lipid A liposomes (MPLA-5) adjuvant (IM)
- **DRUG:** : Investigational product HIV Env Mosaic immunogens MOS1SIP, MOS2SIP, M3SIP8 and Monophosphoryl lipid A liposomes (MPLA-5) adjuvant (IM)

## Key facts

- **NCT ID:** NCT06449196
- **Lead sponsor:** International AIDS Vaccine Initiative
- **Sponsor class:** NETWORK
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2024-08-27
- **Primary completion:** 2025-02-04
- **Final completion:** 2025-02-04
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** Funding withdrawn
- **Last updated:** 2025-03-14

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06449196

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06449196, "Mosaic HIV-1 Envelope Trimer Immunogens Administered to People Living with HIV (PLWH) in Africa". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06449196. Licensed CC0.

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