# Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Colorectal Cancer

> **NCT06449989** · — · RECRUITING · sponsor: **Blokhin's Russian Cancer Research Center** · enrollment: 30 (estimated)

## Conditions studied

- Colorectal Cancer Metastatic
- Brain Metastases, Adult
- Ras (KRAS or NRAS) Gene Mutation
- BRAF Gene Mutation
- HER2 Gene Mutation
- MSI

## Interventions

- **DIAGNOSTIC_TEST:** Tumor samples will be tested for mutation status of KRAS, NRAS, BRAF, HER2 and MSI

## Key facts

- **NCT ID:** NCT06449989
- **Lead sponsor:** Blokhin's Russian Cancer Research Center
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2024-04-01
- **Primary completion:** 2027-09
- **Final completion:** 2027-09
- **Target enrollment:** 30 (ESTIMATED)
- **Last updated:** 2025-08-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06449989

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06449989, "Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Colorectal Cancer". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06449989. Licensed CC0.

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