# SAD of IVT PYC-001 in OPA1 Mutation-Associated Autosomal Dominant Optic Atrophy (Sundew)

> **NCT06461286** · PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **PYC Therapeutics** · enrollment: 18 (estimated)

## Conditions studied

- OPA1 Gene Mutation
- Autosomal Dominant Optic Atrophy
- Hereditary Optic Atrophies
- Kjer Optic Atrophy

## Interventions

- **DRUG:** PYC-001

## Key facts

- **NCT ID:** NCT06461286
- **Lead sponsor:** PYC Therapeutics
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2024-10-31
- **Primary completion:** 2026-08
- **Final completion:** 2026-08
- **Target enrollment:** 18 (ESTIMATED)
- **Last updated:** 2026-01-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06461286

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06461286, "SAD of IVT PYC-001 in OPA1 Mutation-Associated Autosomal Dominant Optic Atrophy (Sundew)". Retrieved via AI Analytics 2026-07-16 from https://api.ai-analytics.org/clinical/NCT06461286. Licensed CC0.

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