# OligoCare TwiCs (Trials Within Cohorts) Trial Comparing Acute Toxicity in Single-fraction vs Multiple-fraction SBRT for Metastasis-directed Treatment (SPRINT)

> **NCT06462963** · NA · RECRUITING · sponsor: **European Organisation for Research and Treatment of Cancer - EORTC** · enrollment: 302 (estimated)

## Conditions studied

- Breast Cancer
- Prostate Cancer
- NSCLC
- Colorectal Cancer
- Oligometastatic Disease

## Interventions

- **RADIATION:** single-fraction SBRT
- **RADIATION:** multiple-fraction SBRT

## Key facts

- **NCT ID:** NCT06462963
- **Lead sponsor:** European Organisation for Research and Treatment of Cancer - EORTC
- **Sponsor class:** NETWORK
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-04-15
- **Primary completion:** 2029-02-15
- **Final completion:** 2029-02-15
- **Target enrollment:** 302 (ESTIMATED)
- **Last updated:** 2025-08-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06462963

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06462963, "OligoCare TwiCs (Trials Within Cohorts) Trial Comparing Acute Toxicity in Single-fraction vs Multiple-fraction SBRT for Metastasis-directed Treatment (SPRINT)". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06462963. Licensed CC0.

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