# Dexmedetomidine-Esketamine Combination for Sedation and Analgesia in ICU Patients

> **NCT06468436** · NA · NOT_YET_RECRUITING · sponsor: **Peking University First Hospital** · enrollment: 1508 (estimated)

## Conditions studied

- Aged
- Intensive Care Units
- Ventilators, Mechanical
- Dexmedetomidine
- Esketamine
- Delirium

## Interventions

- **DRUG:** Dexmedetomidine-Esketamine Combination
- **DRUG:** Dexmedetomidine

## Key facts

- **NCT ID:** NCT06468436
- **Lead sponsor:** Peking University First Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-11
- **Primary completion:** 2029-12-01
- **Final completion:** 2030-12-01
- **Target enrollment:** 1508 (ESTIMATED)
- **Last updated:** 2025-07-31

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06468436

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06468436, "Dexmedetomidine-Esketamine Combination for Sedation and Analgesia in ICU Patients". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT06468436. Licensed CC0.

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