# A Placebo-controlled, Randomized Clinical Trial to Assess the Safety, Feasibility, and Pharmacokinetics of Microbiota Transplant Therapy With Antibiotic Preconditioning and Fiber Supplementation in Patients With Pulmonary Arterial Hypertension

> **NCT06481852** · PHASE1 · RECRUITING · sponsor: **University of Minnesota** · enrollment: 24 (estimated)

## Conditions studied

- Pulmonary Arterial Hypertension

## Interventions

- **DRUG:** MTT with antibiotic preconditioning + fiber supplementation
- **DRUG:** MTT with antibiotic preconditioning + placebo supplementation
- **OTHER:** MTT with placebo + placebo supplementation.

## Key facts

- **NCT ID:** NCT06481852
- **Lead sponsor:** University of Minnesota
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-10-28
- **Primary completion:** 2026-10-31
- **Final completion:** 2027-04-30
- **Target enrollment:** 24 (ESTIMATED)
- **Last updated:** 2025-10-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06481852

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06481852, "A Placebo-controlled, Randomized Clinical Trial to Assess the Safety, Feasibility, and Pharmacokinetics of Microbiota Transplant Therapy With Antibiotic Preconditioning and Fiber Supplementation in Patients With Pulmonary Arterial Hypertension". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06481852. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*